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Ecole Normale Supérieure @ My office
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Last updated: October 6, 2015

As a Biomaterials and Tissue Engineering PhD candidate, Yohan Farouz participated in a translational collaboration and designed the biomaterials currently used as a cardiac patch in the world first clinical trial aiming at delivering human Embryonic Stem Cell-derived cardiac progenitor cells onto the heart of patients with chronic heart failure. He then designed microfabricated assays to question the influence of such biomaterials on the differentiation of pluripotent stem cells into cardiomyocytes.
As a Teaching Assistant and Computer Programmer, Yohan Farouz used computer game development to create and teach a course in biomedical modeling and to mentor students on the development of biological soft matter simulations. In parallel, he designed a smartphone application, EZPaperz, for easier reference management and synchronization on Android. Yohan Farouz is now looking for any opportinity involving innovation at the interface between smart healthcare, regenerative medicine, micro/nanotechnologies and education.
Headline
2011-2015 Sorbonne Paris Cité – Université Paris Descartes
Ph.D. in Biophysics, Biomaterials and Regenerative Medicine

Main area of research: Stem cell and cardiac progenitor cell mechanobiology, Cardiac patches for heart regeneration.
Lab 1: Microfluidics,Nanotechnology (PI: Y. CHEN) CNRS UMR 8640 - Ecole Normale Supe?rieure de Paris
Lab 2: Cell therapy in cardiovascular diseases (PI: Ph. Menasche?) INSERM U970 - HEGP
Doctoral School: Frontie?res du Vivant (FdV) PhD Programme – Centre de Recherches Interdisciplinnaires
2014 Founder at EZBio.net/EZPaperz
EZPaperz is the first android app for synchronizing big digital libraries with Papers, the famous reference management software from Mekentosj.
Scientific Publications
2015 M13 bacteriophage and Adeno-Associated Virus Hybrid for Novel Tissue Engineering Material with Gene Delivery Functions
So Young Yoo, Hyo-Eon Jin, Dong Shin Choi, Masae Kobayashi, Yohan Farouz, Sky Wang, Seung-Wuk Lee
Advanced Healthcare Materials
2014 Growing hearts in the right place: on the design of biomimetic materials for cardiac stem cell differentiation
Yohan Farouz, Yong Chen, André Terzic, Philippe Menasché
Stem Cells published online Dec. 24, 2014
2015 Safety, Regulatory, and Ethical Issues of Human Studies
Yohan Farouz,Mathilde Cossé, Nisa Renault, Philippe Menasché
Chapter from book "Biomaterials in cardiac regeneration".
Springer International Publishing (2015)
2014 Long Term Functional Benefits Of Human Embryonic Stem Cell-Derived Cardiac Progenitors Embedded Into A Fibrin Scaffold
Valérie Bellamy, Valérie Vanneaux, Alain Bel, Hany Nemetalla, Solène Emmanuelle Boitard, Yohan Farouz, Pierre Joanne, Marie-Cécile Perier, Estelle Robidel, Chantal Mandet, Albert Hagège, Patrick Bruneval, Jérôme Larghero, Onnik Agbulut, Philippe Menasché
The Journal of Heart and Lung Transplantation published online Nov. 7, 2014
2014 Towards a clinical use of human embryonic stem cell-derived cardiac progenitors: a translational experience.
Philippe Menasché, Valérie Vanneaux, Jean-Roch Fabreguettes, Alain Bel, Lucie Tosca, Sylvie Garcia, Valérie Bellamy, Yohan Farouz, Julia Pouly, Odile Damour, Marie-Cécile Périer, Michel Desnos, Albert Hagège, Onnik Agbulut, Patrick Bruneval, Gérard Tachdjian, Jean-Hugues Trouvin, Jérôme Larghero
European Heart Journal first published online May 16, 2014
2013 Micropatterning Alginate Substrates for In Vitro Cardiovascular Muscle on a Chip
Ashutosh Agarwal*, Yohan Farouz*, Alexander Peyton Nesmith, Leila F. Deravi, Megan L. McCain, Kevin Kit Parker.*AA and YF contributed equally to this work.
Advanced Functional Materials (2013)
2012 Réparer les coeurs brisés et les vaisseaux abîmés (Mending broken hearts and repairing damaged blood vessels)
Yohan Farouz, Yong Chen, Philippe Menasché, Julia Ino, Michael Atlan, Catherine Le Visage, Didier Letourneur
Biofutur 335, p30-33 (September 2012)
Conference Participations
2013 Mechanical characterization of new clinically relevant fibrin-based hydrogels for heart repair using shear wave ultrasound elastography
Mathieu Pieronne, Mathieu Pernot, Joevin Sourdon, Yong Chen, Alba Marcellan, Philippe Menasche, Yohan Farouz
Oral communication at the MRS Fall Meeting 2013 (December 2013)
2012 Engineering Anisotropic Cardiovascular Muscle on Alginate Surfaces for in vitro Contractility Assays
Ashutosh Agarwal, Yohan Farouz, Alexander Peyton Nesmith, Leila F. Deravi, Megan L. McCain, Kevin Kit Parker.
Oral communication at the MRS Fall Meeting 2012 (November 2012)
2011 Alginate-based muscular thin films for in vitro cardiac contractility assays
Yohan Farouz, Ashutosh Agarwal, Megan L. McCain, Kevin Kit Parker
Oral communication for the MRS Conference 2011 (November 2011)
2011 Alginate-based muscular thin films for in vitro cardiac contractility assays
Yohan Farouz, Ashutosh Agarwal, Megan L. McCain, Kevin Kit Parker
Poster presentation for the BMES Conference 2011 (October 2011)
Invited Talks and Posters
2015 Growing hearts in the right place: on the design of biomimetic materials for cardiac stem cell differentiation.
Yohan Farouz, Yong Chen, Philippe Menasché
Poster presentation at the "Integrative Biology in metabolic and cardiovascular diseases" Summer school, 2015
2014 Translating stem cell mechanobiology to the clinics: high-throughput mechanical characterization of clinically relevant materials for cardiac cell therapy
Yohan Farouz, Pierre Joanne, Mathieu Pieronne, Yong Chen, Philippe Menasché
Oral communication at the Revive Annual Consortium Meeting, 2014
2013 Microengineering materials to study the cardiovascular differentiation of embryonic stem cells and promote their engraftment onto the infarcted myocardium
Yohan Farouz, Yong Chen, Philippe Menasché
Poster presentation at the Annual PARCC retreat, 2013
2013 Microengineering materials to study the cardiovascular differentiation of embryonic stem cells and promote their engraftment onto the infarcted myocardium
Yohan Farouz, Yong Chen, Philippe Menasché
Oral Communication at the Annual Young Researchers' day of the Chemistry Department, ENS Paris, 2013
Entrepreneurship
2014 Founder at EZBio.net
EZBio.net is a platform creating research tools and educational contents for students wanting to break the walls between biology and other disciplines like physics, mathematics, engineering, and software development.
The idea of EZBio.net was born after 3 years of teaching biomedical modeling and data analysis to bachelor and master's students in various Biomedical Engineering programmes.

Expected to be launched in 2015, EZBio.net has released a first side-product in October 2014: EZPaperz.
EZPaperz is the first android app for synchronizing big digital libraries with Papers, the famous reference management software from Mekentosj.
More info on http://ezpaperz.ezbio.net
Teaching Experience
2012-2014 ParisTech/Paris Descartes University - Master in Biomedical Engineering - Teaching Assistant
Courses: Creation and Teaching of the "Biomedical Modeling" Matlab course in the Biomedical Engineering Master Program at Paris Descartes University/ParisTech.
2011-2012 Frontiers in Life Sciences Bachelor Program - Teaching Assistant
Course: Physics and Computer Science
Topics: Solid point mechanics, hydrostatics, fluid dynamics, thermodynamics, basic programming, 'Processing' language.
Interdisciplinary project: The physics behind Angry Birds
Previous Research Experience
2010-2011 Harvard University – Pr. K.K. Parker’s Lab – Research internship
Subject: “Cardiac tissue engineering for integration into a heart-and-lung on a chip system”
Main techniques: soft lithography, micropatterning, cardiomyocyte culture, contractility assays by image processing, AFM, FT-IR, confocal microscopy
2009-2010 Imperial College London – Pr. M. Stevens’s Lab – Master’s research project
Subject: “Design of alginate-based bioactive micro-scaffolds for bone regeneration”
Main techniques: peptide/hydrogel/polymer synthesis, electrospraying, NMR, SEM, protein assays, stem cell culture
2009 Berkeley Lab – Pr. S.W. Lee’s Bio-nanomaterials Lab – Research internship
Subject: “Genetic engineering of new hybrid viral vectors for gene delivery and tissue engineering scaffolds”
Main techniques: bacterial culture, viral amplification, cloning, electrophoresis
2007-2008 Ecole Polytechnique, Paris Saclay – Dr. T. Gacoin’s Condensed Matter Physics Lab - Research Team Project
Subject: “Optimization of the silanisation step in the fabrication of DNA microarrays”
Main techniques: silanisation, mesoporous/sol-gel silica, ATR-IR, colloidal Au assays
Other Work experiences
2006-2007 City and Regional Planning Department of Boulogne-Billancourt City Government (France):
1) Financial and legal consulting for French Private Finance Initiative (PFI) contracts:
->"Design, construction and maintenance of an eco-friendly automated waste collection network in the new boroughs of Boulogne-Billancourt"
->"Design, construction and maintenance of a tramway line accross Boulogne-Billancourt"

2) Computational modeling and statistical consulting for a Regional Master Plan preparation:
->"Statistical analysis of the displacement of the employment barycenter in the Greater Paris Area over the last 13 years. Can we model this evolution and predict future trends?"

2008 Yangshuo and Guilin Backstreet International Youth Hostels (Guangxi, China):
Blue-collar internship consisting in:
- helping the Chinese receptionists by acting as an interpreter between the English-, Spanish-, French-speaking tourists and them.
- cleaning bedrooms
- taking orders/serving breakfasts
Honors and awards
2011-2014 Ecole Doctorale Frontières du Vivant (FdV) - Programme Bettencourt
Training and Traveling awards
2014-2015 Fondation pour la Recherche Medicale
Promising young researcher scholarship
2011-2014 Ecole Polytechnique - Paris Saclay
Scholarship for doctoral research
2010-2011 France Fulbright Scholarship (through Fondation Monahan)
Scholarship for a 10-month research internship at Harvard University
2010 Imperial College London
Master of Science awarded with Distinction
2009-2010 Edward and Eva Underwood Foundation
Scholarship for studies at Imperial College London
2004-2010 Ecole Polytechnique - Paris Saclay
Scholarship for top French engineering students (4 years of funding)
2004 French Baccalauréat with very high honors
Education
2011-2015 Ecole Normale Supérieure de Paris / Paris Descartes University - PhD Candidate
Doctoral School:Frontières du Vivant - Programme Bettencourt (Paris Descartes University)
Lab 1: Group of Microfluidics, Chemical Organisation and Nanotechnology (PI: Pr. Yong CHEN) CNRS UMR 8640 - Ecole Normale Supérieure de Paris
Lab 2: Cell therapy in cardiovascular diseases (PI: Pr. Philippe Menasche) INSERM U970 - Hôpital Européen Georges Pompidou
Main area of research: Stem cell and cardiac progenitor cell mechanobiology, Cardiac patches for heart regeneration.
2009-2010 Imperial College London – Master of Science in Biomedical Engineering with Distinction
Main fields of studies: Biomechanics, Biomaterials, Tissue Engineering
2006-2010 Ecole Polytechnique, Paris Saclay – Master in Engineering
Main fields of studies: Biology, Material Science
2004-2006 Lycée Janson de Sailly (Paris, France): Preparatory Program for French “Grandes Ecoles”
Main fields of studies: Mathematics, Physics and Chemistry
Languages and computer skills
Computer Advanced knowledge in web development, software development and mathematical modeling.
Java, Swift, C++, Matlab, Android dev, Processing P55, HTML/CSS/Javascript, PHP/MySQL, Microsoft Office, VBA...
Languages French: native language
English: fluent (TOEFL iBT : 110/120)
Spanish: fluent
Mandarin Chinese: basic
Outside interests
Music Piano (13 years of conservatory) at the competitive level pre-professional. Composer
Sports Running (marathons), Adventure Racing (Running + Biking + Kayaking), Skiing, Skydiving

Copyright © 2012-2014 Yohan Farouz. All rights reserved.
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